Viral infection and atherosclerosis

Collection Location Koleksi E-book & E-Journal Perpustakaan Pusat Unila
Edition Vol. 37, Issue. 12
Call Number
ISBN/ISSN 1435-4373
Author(s) Hemmat, Nima...[et al.]
Subject(s) Biomedicine
Classification NONE
Series Title
GMD E-Journal
Language English
Publisher Springer
Publishing Year 2018
Publishing Place Switzerland
Collation
Abstract/Notes Abstract
Several risk factors have been described for the pathogenesis of atherosclerosis. Infectious diseases are suggested to be a
causative factor, and some viruses have been studied for their relation with atherosclerotic diseases. Studies report two hypotheses,
direct and indirect effects, for the role of viral infections in atherogenesis. Viruses are able to initiate atherosclerosis by two
different pathways. They can exert their direct effects on atherogenesis by infecting vascular cells and then inducing inflammation
in the endotheliumand smooth muscle cells. Alternatively, they can also apply indirect effects by infecting non-vascular cells
and inducing systemic inflammation. In this review, we consider the available data about the effects and correlations of DNA and
RNA viruses on atherosclerosis.
Keywords Viral infection . Atherosclerosis . Inflammation
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